Doctor-led injectable skin boosters in Oxford for deeper hydration, firmer skin and a healthy glow.
From Profhilo and polynucleotides to PRP, exosomes, mesotherapy, Restylane Vital and SkinVive, our injectable skin boosters rehydrate, repair and refresh your skin from within. Every plan is built and performed by a doctor.
Skin boosters should work with your skin, not change its shape. At Cannelle Skin Clinic in Summertown, Oxford, every booster is matched to your skin and your goal, and we never apply a fixed protocol. Dr Mattia Parducci plans your treatment personally, because the right product and the right number of sessions matter far more than a one-off quick fix.
Each booster does a different job, so choosing well matters as much as the treatment itself. Profhilo spreads hydration and firmness across the whole face. Polynucleotides repair and regenerate thinner, crepey skin. PRP and mesotherapy refresh tone and texture. Skin boosters are not the same as biostimulators such as Sculptra or Radiesse, which rebuild lost volume, whereas boosters improve skin quality rather than restructure the face. The tables below show how the seven boosters compare, so you can find the one that fits your goal before you book.
| At a glance | ProfhiloWhole-face hydration | Restylane VitalDeep micro-hydration | SkinViveCheek smoothing | MesotherapyInstant glow |
|---|---|---|---|---|
 |  |  |  | |
| Best for | Profhilo Overall laxity and dull skin | Restylane Vital Dehydrated face, neck and hands | SkinVive Flat, dry cheeks | Mesotherapy Tired, congested skin |
| What it does | Profhilo Hydrates and firms the whole face | Restylane Vital Deeply hydrates from within | SkinVive Smooths and softens the cheeks | Mesotherapy Refreshes tone and adds glow |
| Key ingredient | Profhilo Pure hyaluronic acid | Restylane Vital Hyaluronic acid micro-droplets | SkinVive Juvederm SkinVive hyaluronic acid | Mesotherapy Vitamin and hyaluronic acid cocktail |
| Sessions | Profhilo Two, a month apart | Restylane Vital Short course of two to three | SkinVive One, topped up over time | Mesotherapy Course of three to six |
| Results last | Profhilo Around six months | Restylane Vital Several months | SkinVive Up to six months | Mesotherapy A few weeks per session |
| Downtime | Profhilo Same day, small bumps settle | Restylane Vital Minimal, brief redness | SkinVive Minimal | Mesotherapy Minimal |
| Reversible | Profhilo Yes, dissolvable | Restylane Vital Yes, dissolvable | SkinVive Yes, dissolvable | Mesotherapy Not applicable |
| Price | Profhilo From £350 | Restylane Vital From £230 | SkinVive £650 | Mesotherapy From £385 |
| View Profhilo | View Restylane Vital | View SkinVive | View mesotherapy |
| At a glance | PolynucleotidesUnder-eye repair | PRP FacialOwn-plasma renewal | ExosomesAdvanced regeneration |
|---|---|---|---|
 |  |  | |
| Best for | Polynucleotides Thin, crepey under-eye skin | PRP Facial Fine lines and dull texture | Exosomes Skin that needs deep renewal |
| What it does | Polynucleotides Repairs and thickens delicate skin | PRP Facial Renews texture and tone | Exosomes Boosts repair after microneedling |
| How it works | Polynucleotides Regenerative polynucleotides | PRP Facial Growth factors from your own plasma | Exosomes Regenerative signals in the skin |
| Sessions | Polynucleotides Course of two to three | PRP Facial Course of three | Exosomes Course, paired with microneedling |
| Results last | Polynucleotides Several months | PRP Facial Several months | Exosomes Assessed at consultation |
| Downtime | Polynucleotides Minimal, small bumps settle | PRP Facial Minimal, brief redness | Exosomes Redness from microneedling for a day |
| Applied by | Polynucleotides Doctor-led injection | PRP Facial Doctor-led injection | Exosomes Therapist, during SkinPen microneedling |
| Price | Polynucleotides From £350 | PRP Facial From £400 | Exosomes At consultation |
| View polynucleotides | View PRP facial | View exosomes |
Every before and after on this page is a real Cannelle Skin Clinic patient, treated at our Oxford clinic. To see the change for yourself, use the slider on the image. Notably, the difference is fresher, healthier skin rather than a change in shape. Of course, results vary from person to person, so every treatment begins with a one to one assessment.
Skinvive
PRP
Restylane
These boosters are not interchangeable. Some flood dull, dehydrated skin with hydration, and here Profhilo, Restylane Vital and mesotherapy do the most work, while SkinVive smooths and softens the cheeks. When the concern is thin, crepey or tired skin, the regenerative options come in. Polynucleotides repair delicate under-eye skin, and PRP renews overall texture and tone.
Many patients get the fullest result from a combination rather than a single product. Our doctor might pair Profhilo for all-over firmness with polynucleotides for the under-eye, or add exosomes during microneedling to deepen the repair. If you are not sure where to start, a consultation is the quickest way to find out, because your skin is assessed in person and matched to the right booster or blend.
Real results come from the right product, the right placement and a properly planned course. That is the standard our medical team holds to at every appointment, in a calm, discreet clinic in the heart of Summertown.
Knowing what to expect makes the whole experience easier. From your first consultation to your follow-up review, every step at Cannelle is doctor-led and unhurried. Open the steps below to see what happens at each stage.
First, the doctor reviews your medical history. Next, they assess your skin type and concern. Then they explain which booster suits your goal and your skin.
Your practitioner agrees the areas, the product and the number of sessions with you. A clear price is confirmed before anything begins, and most boosters work best as a short course.
Using the chosen booster, the doctor injects the area with a fine needle. Topical numbing keeps you comfortable where needed. Most appointments take 20 to 45 minutes.
Some boosters give an immediate glow. Hydration, firmness and repair then build gradually over the following weeks and across your course of sessions.
Once your course is complete, we review your results together and plan any maintenance. Skin-booster results are kept up with occasional top-up sessions.
Book a consultation in Oxford and our doctor will recommend the right booster, the right areas and the right number of sessions. There is never any pressure to decide on the day.
Patients ask us the same questions about skin boosters, so we have answered them here. If anything is still unclear, the doctor will talk it through at your consultation.
At Cannelle Skin Clinic, prices depend on the booster and the number of sessions. Restylane Vital starts from £230, Profhilo and polynucleotides from £350, PRP from £400 and mesotherapy from £385, while SkinVive is £650 including consultation and aftercare, and exosomes are priced at consultation. Because most boosters work best as a course, your practitioner confirms an itemised price before anything begins.
They do different jobs. A skin booster such as Profhilo or polynucleotides improves hydration, firmness and overall skin quality. A dermal filler instead adds shape and volume to a specific area. If rebuilding lost volume is the goal, our biostimulators may suit you better. Because the right choice depends on your skin, the doctor advises at consultation.
It depends on your concern. Profhilo and Restylane Vital suit all-over hydration and firmness, while SkinVive smooths and hydrates the cheeks. Polynucleotides suit thin under-eye skin, while PRP and mesotherapy refresh tone and glow. Because the right choice is rarely obvious, the doctor assesses your skin in person before recommending one.
Yes, that is one of their strongest uses. The under-eye area is thin and delicate, so polynucleotides work well there. They repair and thicken the skin, soften crepiness and improve dark, tired shadows. Many patients choose them specifically for the under-eye over a short course.
Discomfort is mild and manageable. A fine needle and topical numbing are used as needed, and most patients describe a quick pinch at each injection point. Small bumps, mild redness or tiny bruises can occur afterwards and usually settle within a day or two.
It varies by booster. Mesotherapy and PRP give a fresher glow within days. Profhilo and polynucleotides build hydration and firmness over a course and the weeks that follow. Results typically last several months and are kept up with occasional maintenance.
Downtime is minimal for most boosters. You may notice small injection bumps, redness or the odd tiny bruise for a day or two. Most patients return to normal activities the same day, and your practitioner gives you simple aftercare to follow at home.
Yes, and they often are. Because boosters improve skin quality rather than add volume, the doctor may pair them with dermal fillers for structure. They may also be combined with regenerative exosomes, which our therapist applies during microneedling. Your plan can do more than one thing at once.
Every injectable skin booster at Cannelle is planned and performed by Dr Mattia Parducci (GMC: 7635663), a medically qualified doctor. Exosomes are applied by one of our skin therapists during SkinPen microneedling. Either way, your skin is assessed and treated by a trained professional, not a salon technician.
Year after year, our patients return to us for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach at Cannelle Skin Clinic in Oxford.
“I go to Cannelle for facials, manicures and pedicures. They are professional, skilled and attentive to my needs. It is a lovely and relaxing environment. My skin has never looked better.”
“Fantastic. Very welcoming, explained the process and kept me updated throughout, ensuring I was OK. Shared aftercare advice. Would highly recommend and cannot wait to return.”
“What a lovely experience. Maria was brilliant and so professional. She made my appointment comfortable and did a fantastic job. I will definitely be back.”
“Excellent, knowledgeable and impeccable in her attention. The whole experience was the best I have ever had. Will come back.”
Our clinic is located in Summertown, Oxford, just north of the city centre in one of Oxford’s most sought-after neighbourhoods. Discreet and easy to reach, we offer a premium setting for bespoke skin, aesthetic and wellness care.
We welcome patients from across Oxford city and Oxfordshire, including Summertown, Headington, Kidlington, Abingdon, Bicester, Witney and the surrounding towns and villages. Whether you’re coming for routine skin-health treatments or specialist aesthetic consultations, our location is well connected and simple to access.
Our clinic, Cannelle Skin Clinic, is just minutes from Oxford city centre and easily reached by car, bus or rail. Oxford’s mainline stations Oxford Station and Oxford Parkway are a short taxi or bus ride away, and regular services link to London, Reading, Didcot, Banbury and beyond.
By car, we’re conveniently accessed via key local routes with nearby parking options; by public transport, frequent bus routes along Banbury Road drop you within a short stroll of the clinic.
Whether you’re travelling from within Oxfordshire, further afield in the UK or internationally, our clinic offers a calm, personalised and professional environment for your visit.
