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Doctor-led bio-remodelling for the face, neck and hands at Cannelle Skin Clinic in Oxford
Your skin looks drier and flatter than it used to, and no cream seems to bring back the bounce. That is exactly what Profhilo at Cannelle Skin Clinic in Oxford is built to address. It lifts the quality of your skin rather than adding volume, so you get a fresher, healthier complexion while your face stays entirely your own shape.
Profhilo is an injectable treatment made from highly purified hyaluronic acid. It behaves differently from a filler. Instead of sitting in one place to add volume, it spreads through the skin, floods it with hydration and wakes up your own collagen and elastin. Over a short course, your skin becomes firmer, smoother and noticeably more radiant.
Because Profhilo remodels the skin rather than reshaping your face, it refreshes how your skin looks and feels while keeping your features intact. At Cannelle in Oxford, Dr Mattia Parducci plans and performs every treatment personally, so the approach is matched to your skin rather than run off a fixed template.
It is one of our skin booster treatments in Oxford at Cannelle Skin Clinic.

The clever part is a process called bio-remodelling. Dr Mattia places Profhilo at five precise points on each side of the face, known as BAP points, and from there it spreads evenly beneath the skin. That deep hydration prompts your skin to build fresh collagen and elastin, so it firms and refreshes itself from the inside out.
The result grows as your skin regenerates, which is why Profhilo comes as a short course. Most patients begin with two sessions four weeks apart. The improvement in hydration, firmness and glow then keeps developing over the following weeks.
Dr Mattia begins by mapping the five Bio Aesthetic Points on each side of your face. He chooses these positions so the product spreads safely and evenly, sitting well clear of blood vessels and nerves.
He then places a small amount of Profhilo at each point. It is a free-flowing gel rather than a stiff filler, so it starts to disperse through your skin almost straight away.
Once under the skin, Profhilo draws in and holds water, delivering hydration that no cream can reach. Your skin quickly begins to look plumper and more radiant.
Over the following weeks, the hyaluronic acid encourages fresh collagen and elastin. This bio-remodelling effect is what firms and tightens your skin from within.
A second session four weeks later completes the course. Firmness, texture and glow keep improving from there, and the result typically lasts six to nine months.
Most patients arrive at Cannelle in Oxford the moment they notice their skin losing its glow or firmness. From your first consultation to your follow-up, every step is doctor-led and unhurried, so you always know exactly what happens next.

You want to know that the person holding the needle actually understands your skin. At Cannelle, Dr Mattia Parducci (GMC 7635663) performs every Profhilo treatment himself, so safety, precision and a natural result guide each session and you are never handed to a non-medical injector.
Profhilo is an injectable, so who treats you genuinely matters. Every treatment at Cannelle opens with a proper assessment and runs to a medical standard, which keeps the result both safe and natural. If Dr Mattia believes another skin booster would suit you better, he will tell you honestly.

Profhilo at Cannelle Skin Clinic starts from £350 per session. The treatment works best as a short course, so most patients begin with two sessions four weeks apart, then keep it topped up occasionally. Dr Mattia always confirms a clear price at your consultation before anything begins.
Pricing is per session. Most patients begin with a course of two sessions four weeks apart, then keep the result topped up occasionally.
| Treatment | Price (£) |
|---|---|
Profhilo (single session) | £350 |
Profhilo course of 2 (recommended) | £650 |
Profhilo course of 3 | £870 |
Profhilo is one of several skin-quality boosters we offer in Oxford. Depending on what your skin needs, Dr Mattia may suggest comparing or pairing it with polynucleotides, PRP or mesotherapy, each of which improves the skin in its own way.
To see how Profhilo sits alongside our other treatments and find the right option for your skin, visit our skin boosters hub or simply book a consultation and let Dr Mattia guide you.

Patients in Oxford tend to arrive with the same handful of questions about cost, comfort, results and whether Profhilo is right for them. We have answered the most common ones below. If something specific is on your mind, the team is always happy to help, and the clearest answer usually comes from a consultation with Dr Mattia.
Profhilo at Cannelle Skin Clinic starts from £350 per session, with a recommended two-session course at £650. The right plan depends on your skin, so Dr Mattia confirms a clear, itemised price at your consultation before anything begins.
Profhilo suits most adults with dehydrated, dull or early-lax skin who want a natural improvement rather than added volume. Dr Mattia confirms your suitability at a full skin assessment and will point you to a better-fitting treatment if one exists.
Yes. Profhilo is made from highly purified hyaluronic acid, a substance your skin already contains, and it has a strong safety record when given by a qualified doctor. At Cannelle, every treatment is performed by Dr Mattia to a medical standard, which is the single most important safeguard with any injectable.
Most patients see small raised bumps at the injection points, which settle within a day, along with mild redness or tenderness. These effects are short-lived, and Dr Mattia gives you clear aftercare advice so you know exactly what to look out for.
Results typically last six to nine months, depending on your skin and lifestyle. Profhilo improves the skin gradually, so the effect builds over several weeks rather than appearing overnight. A maintenance session once or twice a year keeps your skin looking its best.
Discomfort is usually minimal. Dr Mattia applies numbing cream if you would like it and uses a fine needle at a small number of points, so most patients describe brief scratches rather than anything painful. The session is quick, which keeps it easy to sit through.
For the best result, yes. Profhilo is designed as a course, and two sessions four weeks apart give your skin the hydration and collagen stimulation it needs to firm and glow. After that, a single maintenance session is usually enough to keep the result going.
Initial hydration and glow can show within a couple of weeks. The fuller result, including firmer, smoother skin, builds gradually as new collagen forms and is usually most visible a few weeks after your second session.
Profhilo is most commonly used on the face, and it also works beautifully on the neck, décolletage and the backs of the hands, where skin often looks crepey or dehydrated. Dr Mattia will recommend the right area or combination at your consultation.
Downtime is minimal. Aside from small bumps and mild redness that settle quickly, most patients head straight back into their day. We simply recommend avoiding makeup, heat and strenuous exercise for the first 24 hours.
Once patients understand what Profhilo involves, the next questions are usually about how it stacks up against fillers, polynucleotides and other skin boosters. The answers below cover the comparisons the Cannelle team hears most often about Profhilo in Oxford.
The two do very different jobs. Dermal fillers add volume and reshape features such as the lips or cheeks, while Profhilo improves the quality of the skin itself: hydration, firmness and glow. Profhilo refreshes how your skin looks without touching your proportions, and many patients combine the two for a complete result.
Both are skin boosters, and they work in different ways. Profhilo deeply hydrates and firms lax skin, while polynucleotides focus on repairing and regenerating tired or delicate skin, such as the under-eye area. The best choice comes down to your main concern, so Dr Mattia often recommends one, the other or a combination at your consultation.
Yes. Profhilo is one of the best known skin boosters, a group of injectable treatments that lift skin quality rather than add volume. To see how it compares with our other options, including polynucleotides and PRP, visit our skin boosters hub.
Yes. Many patients at Cannelle combine Profhilo with dermal fillers for volume, or with other skin boosters for an all-round result. These treatments complement one another, so Dr Mattia can plan a sequence that suits your skin and your timescale.
If you want healthier, firmer and more hydrated skin without filler or downtime, Profhilo offers strong value. A short two-session course delivers a natural improvement that lasts several months, and you can maintain the result with a single top-up session each year.
Profhilo relies on correct placement and an honest assessment of whether it is right for you, so the clinician matters. At Cannelle, every treatment is performed by Dr Mattia Parducci, a qualified doctor, and that is what separates a genuinely effective result from a generic one.
You can book a consultation at Cannelle Skin Clinic in Oxford on WhatsApp, by calling 01865 511960, or by booking online. Our Summertown clinic is easy to reach from across Oxfordshire, including Witney, Bicester, Kidlington and Abingdon.
Year after year, our patients in Oxford come back to Cannelle Skin Clinic for natural, healthy-looking results. Every review reflects our commitment to precision, safety and a personalised, doctor-led approach.
Our clinic is located in Summertown, Oxford, just north of the city centre in one of Oxford’s most sought-after neighbourhoods. Discreet and easy to reach, we offer a premium setting for bespoke skin, aesthetic and wellness care.
We welcome patients from across Oxford city and Oxfordshire, including Summertown, Headington, Kidlington, Abingdon, Bicester, Witney and the surrounding towns and villages. Whether you’re coming for routine skin-health treatments or specialist aesthetic consultations, our location is well connected and simple to access.
Our clinic, Cannelle Skin Clinic, is just minutes from Oxford city centre and easily reached by car, bus or rail. Oxford’s mainline stations Oxford Station and Oxford Parkway are a short taxi or bus ride away, and regular services link to London, Reading, Didcot, Banbury and beyond.
By car, we’re conveniently accessed via key local routes with nearby parking options; by public transport, frequent bus routes along Banbury Road drop you within a short stroll of the clinic.
Whether you’re travelling from within Oxfordshire, further afield in the UK or internationally, our clinic offers a calm, personalised and professional environment for your visit.