
Enhance your natural features, restore facial volume, and smooth deep-set lines with expertly applied dermal fillers at our Oxford clinic.
Profhilo Treatment Overview
Profhilo is one of the most advanced injectable skin treatments available, designed to restore hydration, improve elasticity and enhance overall skin quality without altering your natural facial structure. At Cannelle Skin Clinic in Oxford, all Profhilo treatments are performed personally by Dr Mattia Parducci, ensuring a medically led, anatomically precise approach that results in subtle and refined skin rejuvenation.
Unlike dermal fillers, Profhilo does not add volume or contour. Instead, it spreads evenly beneath the skin to stimulate collagen and elastin production. This creates firmer, smoother, more radiant skin that looks refreshed from within rather than cosmetically enhanced. It is an ideal choice for dullness, dehydration, crepey texture and early signs of ageing.
Profhilo is suitable for patients of many ages who want to improve their skin’s quality, particularly on the face, neck, and décolletage. Dr Mattia assesses each patient’s skin and ageing pattern to create a personalised treatment plan that supports long term skin health with natural looking results.


Profhilo contains one of the highest concentrations of pure hyaluronic acid available but behaves differently from traditional fillers. Rather than sitting in one area, it disperses naturally beneath the skin, delivering deep hydration and triggering a bio remodelling effect. This stimulates collagen and elastin production, improving firmness, elasticity and overall vibrancy.
Treatment follows the BAP (Bio Aesthetic Points) technique, which involves injecting small amounts of Profhilo into carefully selected anatomical points on each side of the face. These points allow for safe, even distribution of the product, ensuring comprehensive and consistent improvement across the skin.
Most patients see an early boost in hydration within one to two weeks, followed by visible improvements in texture, softness and overall radiance by week three or four. Two sessions spaced four weeks apart deliver the full effect, with some patients choosing a third treatment for enhanced tightening.
Your Profhilo treatment starts with a consultation with Dr Mattia to assess your skin concerns, hydration levels and the areas most likely to benefit. The injections are placed using the BAP technique, which targets specific points to ensure smooth and even diffusion of the product. The procedure takes around twenty to thirty minutes and small bumps may appear at the injection sites immediately afterwards. These are normal and settle naturally.
Small raised bumps at each injection site are completely expected and typically begin to settle within six to twelve hours. You may also notice slight tenderness or warmth in the treated areas. These effects are short lived, and most patients resume normal activities the same day. Makeup should be avoided for twelve hours to keep the skin clean.
After your treatment, the initial bumps usually settle within the first twelve hours as the product disperses beneath the skin. Over the next week, you may feel your skin becoming more hydrated and soft. Improvements in texture, elasticity and radiance typically appear between weeks three and four. Once the second treatment is completed at around eight weeks, the full effect becomes visible and the skin appears smoother, firmer and more luminous.
Following your Profhilo treatment, avoid touching or massaging the treated areas to allow the product to settle evenly. Intense exercise should be avoided for twenty four hours, and activities involving heat such as steam rooms, saunas or hot yoga should be avoided for forty eight hours. Keep the sites clean and avoid makeup for twelve hours. Applying SPF daily helps support healing and protects the skin as collagen and elastin production increases.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.
I had two waxings and a biofacial today. Holly was excellent, knowledgeable, and impeccable in her attention. The products also felt really lovely – the hot wax was painless and the facial products felt luxurious. The whole experience was the best I’ve ever had. Will come back.
I go to Cannelle for facials, manicures and pedicures. They are professional, skilled, and attentive to my needs. It’s a lovely and relaxing environment. Mursal gives such wonderful treatments. She is very knowledgable about skin care and very gentle in the application of the products. I see her every 6 weeks for a facial and my skin has never looked better.
Patients often come to Cannelle in Oxford wanting to improve their skin without changing their facial features. Profhilo is well suited to those experiencing dullness, dryness or early loss of firmness. A typical journey starts with the first Profhilo session to deeply hydrate and activate the skin’s natural repair processes. Four weeks later, a second session reinforces the result, leading to smoother, brighter and more youthful looking skin.
Many patients choose to maintain their results with a session every six months. Others combine Profhilo with complementary treatments such as microneedling, laser rejuvenation or polynucleotides for a comprehensive skin improvement plan. Treatment pathways are always customised to help achieve the most natural and effective results.
Profhilo provides deep, long lasting hydration that helps the skin look smoother, firmer and more radiant without altering facial structure. It softens fine lines, improves crepey or thinning texture and restores elasticity, giving the skin a healthier, more resilient feel. Because the treatment spreads evenly beneath the surface, it delivers a subtle but significant improvement that enhances natural vibrancy. Patients often describe their skin as fresher, brighter and more youthful within just a few weeks.


“Pricing is per session unless the treatment name includes (x2), (x3), or another session quantity. Multi-session listings represent package pricing.”
All prices are in GBP
Session | Price |
Profhilo | £350 |
Profhilo | £650 |
Profhilo | £870 |
Explore our frequently asked questions from patients in Oxford considering Profhilo treatments.
Profhilo starts from £300 at Cannelle Skin Clinic. Most patients require two sessions four weeks apart for optimal results. View our full pricing guide here.
Profhilo is ideal if you want to improve skin hydration, texture and firmness without adding volume. It suits a wide range of skin types and is particularly beneficial for crepey, dull or dehydrated skin.
Yes. Profhilo uses highly purified hyaluronic acid and has an excellent safety profile. When injected by a medical practitioner such as Dr Mattia, the treatment is both safe and predictable.
Temporary raised bumps at the injection points are normal and usually settle within twelve to twenty four hours. Mild redness or tenderness can occur but fades quickly.
Results typically last around six months. Many patients return every six to nine months to maintain their improved skin quality.
The treatment uses small needles and is generally very tolerable. Some mild stinging may occur, but discomfort is minimal and brief.
Profhilo does not add volume or change facial structure. Instead, it improves hydration, elasticity and overall skin quality. Dermal fillers sculpt, support and contour, while Profhilo revitalises and strengthens the skin.
Profhilo provides deep hydration and bio remodelling through hyaluronic acid, making it ideal for restoring glow and improving texture. Polynucleotides support cell regeneration, healing and repair, helping improve inflammation, scarring and overall skin health. Many patients benefit from using both treatments for a combined regenerative and hydrating effect.
The most common treatment areas include the face, neck and décolletage. It can also improve the appearance of the hands and other regions with crepey skin.
Yes. Two sessions spaced four weeks apart provide the full Profhilo result, with a possible third session recommended for more advanced laxity or dryness.
Choosing Profhilo at Cannelle Skin Clinic means receiving doctor led care from Dr Mattia Parducci, whose medical expertise ensures the treatment is delivered safely and effectively. Based in Oxford, our clinic focuses on achieving natural, healthy looking improvements rather than dramatic changes. We use premium products and clinically proven techniques, while tailoring every plan to your individual skin needs. You will experience a calm, supportive environment where your concerns are listened to and your results are prioritised.


Our clinic is located in Summertown, Oxford, just north of the city centre in one of Oxford’s most sought-after neighbourhoods. Discreet and easy to reach, we offer a premium setting for bespoke skin, aesthetic and wellness care.
We welcome patients from across Oxford city and Oxfordshire, including Summertown, Headington, Kidlington, Abingdon, Bicester, Witney and the surrounding towns and villages. Whether you’re coming for routine skin-health treatments or specialist aesthetic consultations, our location is well connected and simple to access.
Our clinic, Cannelle Skin Clinic, is just minutes from Oxford city centre and easily reached by car, bus or rail. Oxford’s mainline stations Oxford Station and Oxford Parkway are a short taxi or bus ride away, and regular services link to London, Reading, Didcot, Banbury and beyond.
By car, we’re conveniently accessed via key local routes with nearby parking options; by public transport, frequent bus routes along Banbury Road drop you within a short stroll of the clinic.
Whether you’re travelling from within Oxfordshire, further afield in the UK or internationally, our clinic offers a calm, personalised and professional environment for your visit.